Vivofold Research
Microbial Genomics & Antimicrobial Resistance
Antimicrobial resistance is one of the major public-health challenges in India and worldwide. We are building open, reproducible workflows to characterise resistance genes, plasmids and lineages in public bacterial genomes, and to teach them.
Questions
What we want to know
- How well do genotype-based resistance predictions agree with recorded phenotypes in public data?
- Which plasmid backgrounds carry key resistance genes across public Indian isolates?
- How can surveillance analyses be made reproducible for small laboratories?
Approach
How we work on it
- Standardised assembly, typing and resistance detection
- Pangenome and phylogenetic analysis
- Open, documented workflows suitable for teaching
Methods already implemented
MinHash genome similarityPhylogenetic inference with bootstrap support
Open projects
Projects you can join
01
Genotype–phenotype agreement
Compare predicted and recorded resistance in public isolate collections.
02
Plasmid backgrounds of resistance genes
Characterise the mobile elements carrying resistance genes in public genomes.
Across Vivofold
Learn it, use it, commission it
Vedicgen courses
Bacterial Genomics & Antimicrobial ResistanceUp to 4 weeks, about 32 hours live (customisable)Dry labfrom ₹4,499 + GSTMicrobiome & Metagenomics AnalysisUp to 4 weeks, about 32 hours live (customisable)Dry labfrom ₹4,499 + GST
Bioinformatics & Genomics Research Internship Collaborate